Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of legionnaires' disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway

Vitenskapelig artikkel 2016

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151.7 KB

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Engelsk

DOI

https://dx.doi.org/10.1128/genomeA.01367-16

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Marius Dybwad Tone Aarskaug Else-Marie Fykse Elisabeth Henie Madslien Janet Martha Blatny
Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates consisted of a 3.36 Mb-chromosome, while the 2005 genomes featured an additional 68 kb-episome sharing high sequence similarity with the L. pneumophila Lens plasmid. All six genomes contained multiple mobile genetic elements including novel combinations of type-IVA secretion systems. A comparative genomics study will be launched to resolve the genetic relationship between the L. pneumophila isolates.

Utgiverinformasjon

Dybwad, Marius; Aarskaug, Tone; Fykse, Else-Marie; Madslien, Elisabeth Henie; Blatny, Janet Martha. Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of legionnaires' disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. Genome Announcements 2016 ;Volum 4.(6)

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